Charleston, South Carolina, has long been celebrated for its rich history and vibrant culture. In recent years, the city has also become a burgeoning hub for entrepreneurship and small business development. A variety of resources and programs are available to support local entrepreneurs, fostering economic growth and innovation throughout the region.
The Harbor Entrepreneur Center
Located in Mount Pleasant, The Harbor Entrepreneur Center is dedicated to creating connections within the entrepreneurial community. The center offers co-working spaces, mentorship programs, and specialized expertise to help startups and existing businesses thrive. Entrepreneurs can benefit from a dynamic environment designed to enhance productivity and collaboration. Learn more about The Harbor’s offerings.
The Opportunity Center
Situated at 8570 Rivers Avenue in North Charleston, The Opportunity Center is a collaborative effort among four South Carolina nonprofit organizations. This innovative space provides workforce development, small business incubators, and co-working spaces, particularly benefiting entrepreneurs and startups in low-wealth communities. A key component is the Business Success Center, which focuses on helping small business owners and entrepreneurs establish, grow, and sustain their operations, with a special emphasis on communities of color. Explore The Opportunity Center’s initiatives.
City of Charleston’s Small Business Enterprise Office
The City of Charleston’s Small Business Enterprise (SBE) Office empowers small businesses to grow, compete, and participate in the city’s contracting and procurement opportunities. The office assists potential entrepreneurs and existing small business owners through business growth and expansion resources, SBE certification to enhance contracting opportunities, access to financial opportunities, and guidance on management skills and operational effectiveness. Discover more about the SBE Office.
Local Entrepreneur Acceleration Program (LEAP)
Offered by the South Carolina Community Loan Fund, LEAP empowers minority and women entrepreneurs with the tools and resources to grow their businesses. Over a 10-week period, participants gain expert insights on business planning, financial management, and pitching their ideas. Since its inception, LEAP has received 535 applications and awarded over $569,000 in seed capital grants to promising entrepreneurs. Find out more about LEAP.
Charleston Metro Chamber of Commerce
The Charleston Metro Chamber of Commerce provides valuable insights into workforce trends and offers tools to support employers. With a labor force that has grown by nearly 67,000 since 2018, the region continues to experience real competition for talent. The Chamber offers resources to help businesses plan for growth and manage their teams effectively. Read about Charleston’s workforce trends.
By leveraging these resources and programs, Charleston’s entrepreneurs and small business owners can access the support they need to succeed, contributing to the city’s dynamic and growing economy.

